A Voyage Through A Mouse Embryo at 14 days

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• By Nicolas Renier

Description

3D imaging of an 14 days old mouse embryo revealing motor nerves (red) and nociceptive nerves (white), imaged with light sheet microscopy. The motor nerves are visible with an Hb9-GFP transgenic reporter, and the sensory nerves with a TrkA immunolabeling. These images are obtained with the iDISCO tissue clearing and immunolabeling technique. This technique enables the reconstruction of intact biological objects at a cellular resolution. 

Credit: Nicolas Renier, The Rockefeller University