Consciousness and unconsciousness, vision and hallucination, memory and forgetting, sleep, wakefulness, and dream. As much as we have been able to learn about our brains and their functions, particularly in the last century since the advent of modern neuroscience, what we still don't know cover a vast and mysterious territory. For our December issue, we'll probe these fuzzy edges of knowing and unknowing, as neurons attempt self-understanding, neuroscientists search in dreams, and new technologies that allow us deeper glimpses, and even complex modeling, of once-obscure neurological function.