The scientific breakthrough in the 1990s that let us reconstruct the brain’s wiring did so simplifying the anatomy assuming that nerve fibers in each imaging voxel had a single main orientation. With more advanced scanning options and processing options, it became possible to tease out crossing fibers: multiple nerve fibers in one voxel. The single voxel highlighted in this video is an example of where crossing fibers are present, and the reconstructed connections starting from that location are very different when using the initial method (left panel) or the crossing-fibers method (right panel).
Copyright Sjoerd Vos, 2016. Created using ExploreDTI ©